Search results for "QR Microbiology"
showing 10 items of 11 documents
Responses of Saccharomyces cerevisiae Strains from Different Origins to Elevated Iron Concentrations
2015
ABSTRACT Iron is an essential micronutrient for all eukaryotic organisms. However, the low solubility of ferric iron has tremendously increased the prevalence of iron deficiency anemia, especially in women and children, with dramatic consequences. Baker's yeast Saccharomyces cerevisiae is used as a model eukaryotic organism, a fermentative microorganism, and a feed supplement. In this report, we explore the genetic diversity of 123 wild and domestic strains of S. cerevisiae isolated from different geographical origins and sources to characterize how yeast cells respond to elevated iron concentrations in the environment. By using two different forms of iron, we selected and characterized bot…
Post-Transcriptional Regulation of Iron Homeostasis in Saccharomyces cerevisiae
2013
Iron is an essential micronutrient for all eukaryotic organisms because it participates as a redox cofactor in a wide variety of biological processes. Recent studies in Saccharomyces cerevisiae have shown that in response to iron deficiency, an RNA-binding protein denoted Cth2 coordinates a global metabolic rearrangement that aims to optimize iron utilization. The Cth2 protein contains two Cx8Cx5Cx3H tandem zinc fingers (TZFs) that specifically bind to adenosine/uridine-rich elements within the 3' untranslated region of many mRNAs to promote their degradation. The Cth2 protein shuttles between the nucleus and the cytoplasm. Once inside the nucleus, Cth2 binds target mRNAs and stimulate…
Generalization of thermodynamics allowing negentropic entanglement and a model for conscious information processing
2011
Costa de Beauregard considers a model for information processing by a computer based on an analogy with Carnot's heat engine. I am grateful for Stephen Paul King for bringing this article to my attention in Time discussion group and also for inspiring discussions which also led to the birth of this section. As such the model Beauregard for computer does not look convincing as a model for what happens in biological information processing. Combined with TGD based vision about living matter, the model however inspires a model for how conscious information is generated and how the second law of thermodynamics must be modified in TGD framework. The basic formulas of thermodynamics remain as such…
Prevalence and risk factors for Enterobacteriaceae in patients hospitalized with community-acquired pneumonia
2020
N.J.S. is partially funded by the Department of Veterans Affairs, Quality Enhancement Research Initiative (QUERI) Partnered Evaluation Initiative Grant (HX002263-01A1). Background and objective : Enterobacteriaceae (EB) spp. family is known to include potentially multidrug-resistant (MDR) microorganisms, and remains as an important cause of community-acquired pneumonia (CAP) associated with high mortality. The aim of this study was to determine the prevalence and specific risk factors associated with EB and MDR-EB in a cohort of hospitalized adults with CAP. Methods : We performed a multinational, point-prevalence study of adult patients hospitalized with CAP. MDR-EB was defined when ≥3 ant…
Evolution in Many-Sheeted Space-time
2010
The topics of the article has been restricted to those, which seem to represent the most well-established ideas about evolution in many-sheeted space-time. a) Basic facts about and TGD based model for pre-biotic evolution are discussed. b) A model for the ATP-ADP process based on DNA as topological quantum computer vision, the identification of universal metabolic energy quanta in terms of zero point kinetic energies, and the notion of remote metabolism is discussed. c) A model for the evolution of the recent genetic code (3-codons) as a fusion of codes for which codons are nucleotides (1-codons) and di-nucleotides (2-codons) is discussed. The symmetries of the genetic code, the observation…
Quantum Model for Nerve Pulse and EEG
2010
In this article a unified model of nerve pulse and EEG is discussed. a) In TGD Universe the function of EEG and its variants is to make possible communications from the cell membrane to the magnetic body and the control of the biological body by the magnetic body via magnetic flux sheets traversing DNA by inducing gene expression. This leads to the notions of super- and hyper-genome predicting coherent gene expression at level of organs and population. b) The assignment the predicted ranged classical weak and color gauge fields to dark matter hierarchy was a crucial step in the evolution of the model, and led among other things to a model of high T_c superconductivity predicting the basic s…
DNA as Topological Quantum Computer
2010
This article represents a vision about how DNA might act as a topological quantum computer (tqc). Tqc means that the braidings of braid strands define tqc programs and M-matrix (generalization of S-matrix in zero energy ontology) defining the entanglement between states assignable to the end points of strands define the tqc usually coded as unitary time evolution for Schödinger equation. One can ends up to the model in the following manner. a) Darwinian selection for which the standard theory of self-organization provides a model, should apply also to tqc programs. Tqc programs should correspond to asymptotic self-organization patterns selected by dissipation in the presence of metabolic en…
TGD Inspired Model of Living Matter
2009
Basic ideas of TGD inspired view about quantum biology are discussed. TGD inspired theory of consciousness provides the basic conceptual framework besides new view about space-time and quantum theory, in particular dark matter hierarchy whose levels are labelled by the increasing value of Planck constant so that macroscopic quantum systems are predicted to be present in all length scales. This gives a justification for the notion of field body having onion-like fractal structure with astrophysical size and using biological body as a sensory receptor and motor instrument. Great evolutionary leaps correspond naturally to the increases of Planck constant for the highest level in "personal" hie…
Three new physics realizations of the genetic code and the role of dark matter in bio-systems
2010
TGD inspired quantum biology leads naturally to the idea that several realizations of genetic code exist. Besides the realizations based on temporal patterns of electromagnetic �elds I have considered three di�erent new physics realizations of the genetic code based the notions of many- sheeted space-time, magnetic body, and the hierarchy of Planck constants explaining dark matter in TGD framework. 1. The �rst realization - proposed in the model for DNA as topological quantum computer (tqc) - maps the nucleotides A,G and T,C to dark quarks u,d and their anti-quarks assignable to the ends of magnetic ux tubes representing braid strands and connecting nucleotides to lipids of cell membrane. 2…
Model for the Findings about Hologram Generating Properties of DNA
2011
A TGD inspired model for the strange replica structures observed when DNA sample is radiated by red, IR, and UV light using two methods by Peter Gariaev and collaborators. The first method produces what is tentatively interpreted as replica images of either DNA sample or of five red lamps used to irradiate the sample. Second method produce replica image of environment with replication in horizontal direction but only at the right hand side of the apparatus. Also a white phantom variant of the replica trajectory observed in the first experiment is observed and has in vertical direction the size scale of the apparatus. The model is developed in order to explain the characteric features of the…